RAPGEF1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219964A
Immunohistochemistry of paraffin-embedded Human tonsil tissue using RAPGEF1 Polyclonal Antibody at dilution of 1:45(×200)
Variation
Quantity
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Overview
Product Name
RAPGEF1 Polyclonal Antibody
Catalog Number
RD219964A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Immunogen Information
Immunogen
Synthetic peptide of human RAPGEF1
Swissprot
Q13905
Synonyms
C3GC3G proteinCRK SH3 binding GNRPCRK SH3-binding GNRPDKFZp781P1719GRF 2GRF2Guanine nucleotide releasing factor 2 (specific for crk proto oncogene)Guanine nucleotide releasing factor 2Guanine nucleotide-releasing factor 2OTTHUMP00000064558Prote
Gene Accession
NP005303
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
1.32 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas