Guanine nucleotide exchange factor (GEF for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity.
Immunogen Information
Immunogen
Recombinant fusion protein of human RAPGEF4
Gene ID
11069
Swissprot
Q8WZA2
Synonyms
RAPGEF4CAMP-GEFIICGEF2EPACEPAC 2EPAC2Nbla00496
Calculated MW
35kDa/106kDa
Observed MW
135kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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