This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
Immunogen Information
Immunogen
Recombinant protein of human RARA
Swissprot
P10276
Synonyms
NR1B1Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion proteinNuclear receptor subfamily 1 group B member 1Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long formRAR alphaRARRAR-alphararaRARARARalphaRARalp
Gene Accession
BC008727
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4