This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A whicHuman, Mouseediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined.
Immunogen Information
Immunogen
Recombinant protein of human RARB
Swissprot
P10826
Synonyms
HAPHBV-activated proteinNR1B2Nuclear receptor subfamily 1 group B member 2RAR BRAR betaRAR epsilonRAR-betaRAR-epsilonRARBRARBRetinoic acid receptor beta 2Retinoic acid receptor beta 4Retinoic acid receptor beta 5Retinoic acid receptor betaR
Calculated MW
50 kDa
Gene Accession
BC060794
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4