RASA2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77086A
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using RASA2 Polyclonal Antibody at dilution 1:45
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using RASA2 Polyclonal Antibody at dilution 1:45
Product Name
RASA2 Polyclonal Antibody
Catalog Number
RD77086A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein; a compound suggested to function as a second messenger.
Immunogen Information
Immunogen
Synthetic peptide of human RASA2
Swissprot
Q15283
Synonyms
GAP1mGTPase activating protein of RASRas GTPase activating protein 2Ras GTPase-activating protein 2RAS p21 protein activator 2Rasa2RASA2
Gene Accession
NP_006497
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas