RASSF7 (Ras association domain-containing protein 7), also designated HRAS1-related cluster protein 1, is a 373 amino acid protein that localizes to the centrosome. RASSF7, RASSF8, RASSF9 and RASSF10 are four evolutionary conserved proteins that are collectively known as the N-terminal RASSF family. Expressed in skin, neural tube and eye, RASSF7 is believed to play an essential role in mitosis. Further supporting its mitotic role, knockdown of Xenopus RASSF7 has been shown to influence cell failure to form mitotic spindle and also cause nuclear breakdown and apoptosis.
Immunogen Information
Immunogen
Recombinant protein of human RASSF7
Swissprot
Q02833
Synonyms
C11orf13Chromosome 11 open reading frame 13HRAS1HRAS1 related cluster 1HRAS1 related cluster protein 1HRAS1-related cluster protein 1HRC1MGC126069MGC126070Ras association (RalGDS/AF 6) domain family (N terminal) member 7Ras association (RalGDS/A
Calculated MW
40 kDa
Gene Accession
BC106921
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4