RBM15 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD267632A
Western blot analysis of extracts of various cell lines using RBM15 Polyclonal Antibody at dilution of 1:1000.
Variation
Quantity
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Overview
Product Name
RBM15 Polyclonal Antibody
Catalog Number
RD267632A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family,which have repressor function in several signaling pathway,and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t(1,22)(p13;q13) infant acute megakaryocytic leukemia,and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation,which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation,block the cell cycle,and induce apoptosis in CML cells.
Immunogen Information
Immunogen
Recombinant fusion protein of human RBM15 (NP_001188474.1).
Gene ID
64783
Swissprot
Q96T37
Synonyms
RBM15OTTOTT1SPEN
Calculated MW
99 kDa/104 kDa/106 kDa/107 kDa
Observed MW
120 kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas