RBM4 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD253174A
Western blot analysis of Hela and MCF7 cell lysates  using RBM4 Polyclonal Antibody at dilution of 1:750
Western blot analysis of Hela and MCF7 cell lysates using RBM4 Polyclonal Antibody at dilution of 1:750
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For more information on our kits, please contact us at info@reddotbiotech.com

Overview

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Product Name
RBM4 Polyclonal Antibody
Catalog Number
RD253174A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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RBM4,RNA-binding motif protein4,contains 2 RRM-type RNA-binding motif and a retroviral-type(RT) zinc finger. RNA-binding factor participates in number of aspects of cellular processes such as alternative splicing of pre-mRNA and translation regulation. RBM4 recruits eIF4A1 to stimulate IRES-dependent translation in responds to cellular stress. Once assembled at the rHRE,the HIF2A-RBM4-eIF4E2 complex captures the 5-prime cap and targets mRNAs to polysomes for active translation,thereby evading hypoxia-induced repression of protein synthesis.

Immunogen Information

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Immunogen
Fusion protein of human RBM4
Swissprot
Q9BWF3
Synonyms
dkfzp547k0918hLarklarkLark homologlark homologuemgc75138RBM4rbm4 larkRBM4RNA binding motif 4RNA binding motif 4aRNA-binding motif protein 4RNA-binding motif protein 4aRNA-binding protein 4
Calculated MW
40 kDa
Observed MW
Refer to figures
Gene Accession
BC032735

Applications

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Reactivity
Human, Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Concentration
0.66 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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