This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
Immunogen Information
Immunogen
Recombinant protein of human RBM5
Swissprot
P52756
Synonyms
FLJ39876G15H37LUCA 15LUCA15Protein G15Putative tumor suppressor LUCA15RBM 5Rbm5RBM5Renal carcinoma antigen NY REN 9Renal carcinoma antigen NY-REN-9RMB 5RMB5RNA binding motif protein 5RNA binding protein 5RNA-binding motif protein 5RNA-bin
Calculated MW
92 kDa
Gene Accession
BC002957
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:25-1:100
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4