For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86994A
Western blot detection of ABCE1 in K562,C6,3T3,Hela cell lysates using ABCE1 Rabbit mAb(1:1000 diluted).Predicted band size:67kDa.Observed band size:67kDa.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
Immunogen Information
Immunogen
A synthetic peptide of human ABCE1
Gene ID
6059
Swissprot
P61221
Synonyms
2' 5' oligoadenylate binding protein2''-5''-oligoadenylate-binding protein2'5' oligoadenylate binding proteinABC 38ABC38ABCE 1ABCE1ABCE1ATP binding cassette sub family E (OABP) member 1ATP binding cassette sub family E member 1ATP-binding casset
Calculated MW
44kDa
Observed MW
44kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.