Recombinant ALDH1A1 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86907A
Western blot detection of ALDH1A1 in K562,3T3 cell lysates using ALDH1A1 Rabbit mAb(1:1000 diluted).Predicted band size:55kDa.Observed band size:55kDa.
Immunohistochemistry of ALDH1A1 in paraffin-embedded Human Cholangiocarcinoma using ALDH1A1 Rabbit mAb at dilution 1:20
Product Name
Recombinant ALDH1A1 Monoclonal Antibody
Catalog Number
RD86907A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
ALDH1A1(Aldehyde dehydrogenase family 1 member A1 ),also named as ALDC,ALDH1 and PUMB1,belongs to the aldehyde dehydrogenase family. The ALDH1A1 gene encodes a liver cytosolic isoform of acetaldehyde dehydrogenase,an enzyme involved in the major pathway of alcohol metabolism after alcohol dehydrogenase. ALDH1A1 plays a critical role in protection against oxidative stress-induced cytotoxicity in lens epithelial cells. And it is important for multiple biological activities including drug resistance,cell differentiation,and oxidative stress response. As a novel cancer stem cell marker,ALDH1A1 can be used for tumors whose corresponding normal tissues express ALDH1A1 in relatively restricted or limited levels such as breast,lung,ovarian or colon cancer.
Immunogen Information
Immunogen
A synthetic peptide of human ALDH1A1
Gene ID
216
Swissprot
P00352
Synonyms
ALDH1A1ALDCALDH-E1ALDH1ALDH11HEL-9HEL-S-53eHEL12PUMB1RALDH1
Calculated MW
84kDa
Observed MW
84kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC-P
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000, IHC 1:20-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas