Recombinant Angiotensin II Type 1 Receptor Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87001A
Western blot detection of Angiotensin II Type 1 Receptor in HepG2 cell lysates using Angiotensin II Type 1 Receptor Rabbit mAb(1:1000 diluted).Predicted band size:41kDa.Observed band size:41kDa.
Product Name
Recombinant Angiotensin II Type 1 Receptor Monoclonal Antibody
Catalog Number
RD87001A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Angiotensin II (Ang II),the main effector molecule of the renin-angiotensin system,exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1,also named as AT1R),thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone,cardiovascular function,salt and water homeostasis,AGTR1 exerts an indispensable physiological role . AGTR1 has been implicated in diverse aspects of human disease,from the regulation of blood pressure and cardiovascular homeostasis to cancer progression .
Immunogen Information
Immunogen
A synthetic peptide of human Angiotensin II Type 1 Receptor
Gene ID
185
Swissprot
P30556
Synonyms
AGTR1AG2SAGTR1BAT1AT1ARAT1BAT1BRAT1RAT2R1HAT1R
Calculated MW
312kDa
Observed MW
160kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas