Recombinant beta Catenin Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86918A
Western blot detection of beta Catenin in C6,CHO-K1,Hela cell lysates using beta Catenin Rabbit mAb(1:1000 diluted).Predicted band size:86kDa.Observed band size:86kDa.
Immunohistochemistry of beta Catenin in paraffin-embedded Human Cholangiocarcinoma using beta Catenin Rabbit mAb at dilution 1:50
Product Name
Recombinant beta Catenin Monoclonal Antibody
Catalog Number
RD86918A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
CTNNB1,also known as β-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
Immunogen Information
Immunogen
A synthetic peptide of human beta Catenin
Gene ID
1499
Swissprot
P35222
Synonyms
Beta cateninBeta-cateninCadherin associated proteinCatenin (cadherin associated protein)beta 188kDaCatenin beta 1Catenin beta-1CATNBCHBCATCTNB1CTNNBCTNNB1DKFZp686D02253FLJ25606FLJ37923OTTHUMP00000162082OTTHUMP00000165222OTTHUMP0000016522
Calculated MW
41kDa
Observed MW
41kDa
Applications
Reactivity
Human,Mouse,Rat,Hamster
Tested Applications
WB,IHC-P
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000, IHC 1:50-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.