Recombinant Caspase 8 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87013A
Western blot detection of Caspase-8 in CHO-K1 cell lysates using Caspase-8 Rabbit mAb(1:500 diluted).Predicted band size:55kDa.Observed band size:55kDa.
Product Name
Recombinant Caspase 8 Monoclonal Antibody
Catalog Number
RD87013A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Caspase 8,also named as MCH5,MACH,FLICE,and CAP4,belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. Caspase 8 Monoclonal Antibody can recognize pro- and cleaved-caspase 8.
Immunogen Information
Immunogen
A synthetic peptide of human Caspase-8
Gene ID
841
Swissprot
Q14790
Synonyms
ALPS2BAmyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 proteinApoptotic cysteine proteaseApoptotic protease Mch-5Apoptotic protease Mch5CAP4CASP-8CASP8CASP8Caspase 8Caspase 8 apoptosis related cysteine peptidaseCaspase-8 sub
Calculated MW
46kDa
Observed MW
46kDa
Applications
Reactivity
Hamster
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas