Recombinant CD31 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western blot detection of CD31 in Jurkat cell lysates using CD31 Rabbit mAb(1:500 diluted).Predicted band size:83kDa.Observed band size:130kDa.
Immunohistochemistry of CD31 in paraffin-embedded Human lung cancer tissue using CD31 Rabbit mAb at dilution 1/50
Product Name
Recombinant CD31 Monoclonal Antibody
Catalog Number
RD86935A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Platelet endothelial cell adhesion molecule-1 (PECAM-1,CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. It is highly expressed on the surface of the endothelium,making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets,monocytes,neutrophils,natural killer cells,megakaryocytes and some types of T-cell . As well as its role in cell-cell adhesion,PECAM-1 functions as a signaling receptor,and is involved in important physiological events such as nitric oxide production,regulation of T-cell immunity and tolerance,leukocyte transendothelial migration and inflammation and angiogenesis .
Immunogen Information
Immunogen
A synthetic peptide of human CD31
Gene ID
5175
Swissprot
P16284
Synonyms
Adhesion moleculeCD31CD31 antigenCD31 EndoCAMEndoCAMFLJ34100FLJ58394GPIIAGPIIA'PECA1PECA1Pecam 1PECAM 1 CD31 EndoCAMPECAMPECAM-1Pecam1Platelet and endothelial cell adhesion molecule 1Platelet endothelial cell adhesion moleculePlatelet/en
Calculated MW
139kDa
Observed MW
150kDa
Applications
Reactivity
Human
Tested Applications
WB,IHC-P
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:20-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas