Recombinant CLSTN1 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western blot detection of CLSTN1 in Hela,CHO-K1 cell lysates using CLSTN1 Rabbit mAb(1:1000 diluted).Predicted band size:110kDa.Observed band size:110kDa.
Immunohistochemistry of CLSTN1 in paraffin-embedded Human colon cancer tissue using CLSTN1 Rabbit mAb at dilution 1:50
Product Name
Recombinant CLSTN1 Monoclonal Antibody
Catalog Number
RD87020A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Calsyntenins (calsyntenin-1, -2, -3) compose a family of neuronally expressed proteins that belong to the cadherin superfamily of cell adhesion molecules (PMID: 24966372; 12498782). Calsyntenin-1 (CLSTN1) is a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain. By binding Ca2+, calsyntenin-1 may modulate Ca2+-mediated postsynaptic signals (PMID: 11161476). Calsyntenin-1 is a transmembrane cargo-docking protein for Kinesin-1-mediated vesicular transport (PMID: 16760430). It can mediate axonal transport of the amyloid precursor protein and regulate Aβ production
Immunogen Information
Immunogen
A synthetic peptide of human CLSTN1
Gene ID
22883
Swissprot
O94985
Synonyms
CST-1CSTN1CDHR12PIK3CDALC-ALPHAXB31alphaalcalpha1alcalpha2
Calculated MW
19kDa
Observed MW
19kDa
Applications
Reactivity
Human,Mouse,Hamster
Tested Applications
WB,IHC-P
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.