Recombinant Cytochrome P450 2D6 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86973A
Western blot detection of CYP2D6 in Hela,A549,HL-60,U251,U87-MG cell lysates using CYP2D6 Rabbit mAb(1:1000 diluted).Predicted band size:56kDa.Observed band size:50kDa.
Immunohistochemistry of CYP2D6 in paraffin-embedded liver cancer tissue using CYP2D6 Rabbit mAb at dilution 1:50
Immunofluorescence of CYP2D6(green) in hela using CYP2D6 Rabbit mAb at dilution 1:50, and DAPI(blue)
Product Name
Recombinant Cytochrome P450 2D6 Monoclonal Antibody
Catalog Number
RD86973A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
CYP2D6(Cytochrome P450 2D6) is also named as CYP2DL1 and belongs to the cytochrome P450 family. It is a monooxygenase that involved in the metabolism of drugs such as antiarrhythmics,adrenoceptor antagonists,and tricyclic antidepressants. CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.
Immunogen Information
Immunogen
Recombinant protein of human CYP2D6
Gene ID
1565
Swissprot
P10635
Synonyms
CPD6CYP2DCYP2D6CYP2D7APCYP2D7BPCYP2D7P2CYP2D8P2CYP2DL1CYPIID6Cytochrome P450 DB1Cytochrome P450 family 2 subfamily D member 6Cytochrome P450 family 2 subfamily D polypeptide 6Debrisoquine 4 hydroxylaseFlavoprotein linked monooxygenaseMicroso
Calculated MW
104kDa
Observed MW
124/114kDa
Applications
Reactivity
Human
Tested Applications
WB,IHC-P,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, IF 1:50-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas