Recombinant FAK Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86941A
Western blot detection of FAK in K562,C6,3T3,Hela cell lysates using FAK Rabbit mAb(1:1000 diluted).Predicted band size:119kDa.Observed band size:125kDa.
Immunohistochemistry of FAK in paraffin-embedded Human colon cancer tissue using FAK Rabbit mAb at dilution 1:50
Product Name
Recombinant FAK Monoclonal Antibody
Catalog Number
RD86941A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
FAK (Focal adhesion kinase 1) is also named as FAK1,FADK,pp125FAK,FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion,migration,proliferation and survival in response to extracellular signals . It also acts as a pivotal signal 'integrator',controlling and coordinating cellular responses that include cell migration,survival,proliferation and,epithelial tissue repair after DNA damage . This protein has 6 isoforms produced by alternative promoter usage and alternative splicing.
Immunogen Information
Immunogen
A synthetic peptide of human FAK
Gene ID
5747
Swissprot
Q05397
Synonyms
FADK 1FADKFAK related non kinase polypeptideFAK1FAK1Focal adhesion kinase 1Focal adhesion KinaseFocal adhesion kinase isoform FAK Del33Focal adhesion kinase related nonkinaseFRNKp125FAKpp125FAKPPP1R71Protein phosphatase 1 regulatory subunit 7
Calculated MW
52kDa
Observed MW
52kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-P
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000, IHC 1:50-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas