Recombinant FKBP52 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86942A
Western blot detection of FKBP52 in Jurkat,C6,CHO-K1,Hela cell lysates using FKBP52 Rabbit mAb(1:500 diluted).Predicted band size:52kDa.Observed band size:52kDa.
Immunofluorescence of FKBP52 (green) in hela using FKBP52 Rabbit mAb at dilution 1:50, and DAPI(blue)
Product Name
Recombinant FKBP52 Monoclonal Antibody
Catalog Number
RD86942A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.
Immunogen Information
Immunogen
A synthetic peptide of human FKBP52
Gene ID
2288
Swissprot
Q02790
Synonyms
51 kDa FK506-binding protein52 kDa FK506 binding protein52 kDa FK506-binding protein52 kDa FKBP59 kDa immunophilinFK506 binding protein 4FK506-binding protein 4FKBP 4FKBP 52FKBP 59FKBP-4FKBP-52FKBP4FKBP4FKBP51FKBP52 proteinFKBP59HBIHsp 5
Calculated MW
58kDa
Observed MW
58kDa
Applications
Reactivity
Human,Mouse,Rat,Hamster
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IF 1:20-1:50
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas