Recombinant GSDMD Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86946A
Western blot detection of GSDMD in Jurkat cell lysates using GSDMD Rabbit mAb(1:500 diluted).Predicted band size:53kDa.Observed band size:53kDa.
Product Name
Recombinant GSDMD Monoclonal Antibody
Catalog Number
RD86946A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently,GSDMD is identified as a new component of inflammasomes,and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Immunogen Information
Immunogen
Recombinant protein of human GSDMD
Gene ID
79792
Swissprot
P57764
Synonyms
DF5LDFNA5LFKSG10GSDMDC1GSDMD
Calculated MW
102kDa
Observed MW
102kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas