Western blot detection of GSK3 beta in Jurkat,C6,CHO-K1,Hela cell lysates using GSK3 beta Rabbit mAb(1:1000 diluted).Predicted band size:47kDa.Observed band size:47kDa.
Immunohistochemistry of GSK3 beta in paraffin-embedded Human Cholangiocarcinoma using GSK3 beta Rabbit mAb at dilution 1:20
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.