Recombinant Integrin beta 5 Monoclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Western blot detection of Integrin beta 5 in C6,CHO-K1,Hela cell lysates using Integrin beta 5 Rabbit mAb(1:500 diluted).Predicted band size:88kDa.Observed band size:88kDa.
Western blot detection of Integrin beta 5 in C6,CHO-K1,Hela cell lysates using Integrin beta 5 Rabbit mAb(1:500 diluted).Predicted band size:88kDa.Observed band size:88kDa.
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For more information on our kits, please contact us at info@reddotbiotech.com

Overview

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Product Name
Recombinant Integrin beta 5 Monoclonal Antibody
Catalog Number
RD87047A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors.

Immunogen Information

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Immunogen
Recombinant protein of human Integrin beta 5
Gene ID
3693
Swissprot
P18084
Synonyms
FLJ26658Integrin beta-5Integrin subunit beta 5integrinbeta 5ITB5Itgb5Testis secretory sperm-binding protein Li 217p
Calculated MW
54kDa
Observed MW
54kDa

Applications

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Reactivity
Human,Rat,Hamster
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Research Areas

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