This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Immunogen Information
Immunogen
A synthetic peptide of human JAK2
Gene ID
3717
Swissprot
O60674
Synonyms
JAK 2JAK-2JAK2JAK2Janus Activating Kinase 2Janus kinase 2 (a protein tyrosine kinase)Janus kinase 2JTK 10JTK10kinase Jak2OTTHUMP00000043260THCYT3Tyrosine protein kinase JAK2Tyrosine-protein kinase JAK2
Calculated MW
48/53kDa
Observed MW
46/54kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.