This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
Immunogen Information
Immunogen
A synthesized peptide derived from human KDM4A / JHDM3A / JMJD2A
Gene ID
9682
Swissprot
O75164
Synonyms
JHDM3AJmjC domain containing histone demethylation protein 3AJmjC domain-containing histone demethylation protein 3AJMJD2JMJD2Ajumonji C domain containing histone demethylase 3AJumonji domain containing 2Jumonji domain containing 2AJumonji domain
Calculated MW
74 kDa
Observed MW
74/63 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.