Western blot detection of Leukotriene A4 hydrolase/LTA4H in K562,C6,3T3,Hela cell lysates using Leukotriene A4 hydrolase/LTA4H Rabbit mAb(1:1000 diluted).Predicted band size:69kDa.Observed band size:69kDa.
Immunohistochemistry of Leukotriene A4 hydrolase in paraffin-embedded Human tonsil using Leukotriene A4 hydrolase Rabbit mAb at dilution 1:50
LTA4H (Leukotriene A4-hydrolase ) is a Zn2+-containing enzyme with both epoxide hydrolase and aminopeptidase activity. As an epoxide hydrolase, LTA4H catalyzes the hydration of LTA4 to leukotriene B4 (LTB4, 5S,12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid), a potent lipid chemoattractant that influences inflammation, immune responses, and host defense against infection. As an aminopeptidase, LTA4H catalyzes the cleavage of amides of para-nitroaniline. The human LTA4H gene encodes a 610 amino acid protein.
Immunogen Information
Immunogen
A synthetic peptide of human Leukotriene A4 hydrolase