Recombinant P2Y12 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87064A
Western blot detection of P2Y12 in A549,HL-60,U251,U87-MG cell lysates using P2Y12 Rabbit mAb(1:1000 diluted).Predicted band size:40kDa.Observed band size:52kDa.
Product Name
Recombinant P2Y12 Monoclonal Antibody
Catalog Number
RD87064A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.
Immunogen Information
Immunogen
A synthetic peptide of human P2Y12
Gene ID
64805
Swissprot
Q9H244
Synonyms
P2RY12ADPG-RBDPLT8HORK3P2T(AC)P2Y(12)RP2Y(AC)P2Y(ADP)P2Y(cyc)P2Y12SP1999
Calculated MW
44kDa
Observed MW
53kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.