Recombinant PRMT7 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87073A
Western blot detection of PRMT7 in K562,3T3,Hela cell lysates using PRMT7 Rabbit mAb(1:1000 diluted).Predicted band size:79kDa.Observed band size:79kDa.
Variation
Quantity
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Overview
Product Name
Recombinant PRMT7 Monoclonal Antibody
Catalog Number
RD87073A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine(AdoMet) as the methyl donor. Arginine methylation is implicated insignal transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).
Immunogen Information
Immunogen
A synthetic peptide of human PRMT7
Gene ID
54496
Swissprot
Q9NVM4
Synonyms
[Myelin basic protein]-arginine N-methyltransferase PRMT7ANM7FLJ10640Histone-arginine N-methyltransferase PRMT7KIAA1933Myelin basic protein arginine N methyltransferaseOTTHUMP00000174863PRMT7Protein arginine methyltransferase 7Protein arginine N-
Calculated MW
30 kDa
Observed MW
30 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas