Western blot detection of VEGF Receptor 1 in K562,C6,3T3,Hela cell lysates using VEGF Receptor 1 Rabbit mAb(1:1000 diluted).Predicted band size:151kDa.Observed band size:180kDa.
Immunohistochemistry of VEGF Receptor 1 in paraffin-embedded Human colon cancer tissue using VEGF Receptor 1 Rabbit mAb at dilution 1:50
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
Immunogen Information
Immunogen
A synthetic peptide of human VEGF Receptor 1
Gene ID
2321
Swissprot
P17948
Synonyms
EC 2.7.10.1FLT 1FLTFlt-1FLT1Fms like tyrosine kinase 1Fms related tyrosine kinase 1Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)Fms related tyrosine kinase 1 vascular endothelial growth fa
Calculated MW
124kDa
Observed MW
124kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-P
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.