Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
Immunogen Information
Immunogen
Fusion protein of human RGS2
Swissprot
P41220
Synonyms
Basic helix-loop-helix phosphoprotein G0S8Cell growth inhibiting protein 31Cell growth-inhibiting gene 31 proteinG0 to G1 switch regulatory 8 24kDG0/G1 switch regulatory protein 8G0S8GOS8OTTHUMP00000060765Regulator of G protein signaling 2Regulat