RGS22 (regulator of G-protein signaling 22), also known as FLJ75004, PRTD-NY2, FLJ40080, MGC102908 or DKFZp434I092, is a novel 1264 amino acid regulator of G-protein signaling specific to to testis. RGS22 inhibits signal transduction and contains two isoforms as a result of alternative splicing. RGS22 is found in spermatogenic cells and Leydig cells, and may be involved in the translocation of GNA13 from the cytoplasm to the nucleus during spermiogenesis. RGS22 contains two RGS domains: RGS1 and RGS2, and the gene encoding RGS22 maps to human chromosome 8q22.2.
Immunogen Information
Immunogen
Recombinant protein of human RGS22
Swissprot
Q8NE09
Synonyms
FLJ40080FLJ75004MGC102908PRTD-NY2Regulator of G-protein signaling 22RGS22RGS22
Calculated MW
147 kDa
Gene Accession
BC047060
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4