The protein encoded by this gene is a member of the rhomboid family of integral membrane proteins. This family contains proteins that are related to Drosophila rhomboid protein. Members of this family are found in both prokaryotes and eukaryotes and are thought to function as intramembrane serine proteases. The encoded protein is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 and ephrin B3. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Fusion protein of human RHBDL2
Swissprot
Q9NX52
Synonyms
MGC16997RHBDL2Rhomboid like protein 2Rhomboid related protein 2Rhomboid veinlet like 2 (Drosophila)RRP2