This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Immunogen Information
Immunogen
Synthetic peptide of human RHEB
Swissprot
Q15382
Synonyms
Ras homolog enriched in brain 2formerlyGTP binding protein RhebGTP-binding protein RhebMGC111559Ras homolog enriched in brain 2Ras homolog enriched in brainRHEB 2RhebRHEBRHEB2RHEB2formerly
Gene Accession
NP_005605
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4