RHOB Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD266931A
Western blot analysis of extracts of Mouse brain using RHOB Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of Mouse brain using RHOB Polyclonal Antibody at dilution of 1:1000.
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Overview

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Product Name
RHOB Polyclonal Antibody
Catalog Number
RD266931A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

Immunogen Information

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Immunogen
A synthetic peptide of human RHOB (NP_004031.1).
Gene ID
388
Swissprot
P62745
Synonyms
RHOBARH6ARHBMST081MSTP081RHOH6
Calculated MW
22 kDa
Observed MW
22 kDa

Applications

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Reactivity
Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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