RICTOR Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75545A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using RICTOR Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using RICTOR Polyclonal Antibody at dilution 1:50
Product Name
RICTOR Polyclonal Antibody
Catalog Number
RD75545A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Rapamycin-insensitive companion of mTORis aproteinthat in humans is encoded by theRICTORgene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.
Immunogen Information
Immunogen
Recombinant protein of human RICTOR
Swissprot
Q6R327
Synonyms
AVO3AVO3 homologDKFZp686B11164hAVO3KIAA1999Likely ortholog of mouse TORC2 specific protein AVO3 (S. cerevisiae)mAVO3MGC39830PIAPianissimoRapamycin insensitive companion of mTORRapamycin-insensitive companion of mTORRictorRICTRRICTRRPTOR ind
Gene Accession
BC029608
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas