Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase. May also function as an endoribonuclease, cleaving mRNA phosphodiester bonds of single-stranded RNA (By similarity). Thereby, may inhibit protein translation (PubMed:8973653).
Immunogen Information
Immunogen
Fusion protein of human RIDA
Swissprot
P52758
Synonyms
14.5 kDa translational inhibitor protein2-iminobutanoate/2-iminopropanoate deaminaseHeat responsive protein 12Heat-responsive protein 12Hrsp12p14.5Perchloric acid soluble proteinPSPReactive intermediate imine deaminase A homologRibonuclease UK114