RITA1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253132A
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using RITA1 Polyclonal Antibody at dilution of 1:50(×200)
Product Name
RITA1 Polyclonal Antibody
Catalog Number
RD253132A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Immunogen Information
Immunogen
Fusion protein of human RITA1
Swissprot
Q96K30
Synonyms
C12orf52Chromosome 12 open reading frame 52RBPJ interacting and tubulin associated 1RBPJ interacting and tubulin associated protein 1RBPJ-interacting and tubulin-associated proteinRITARITA
Gene Accession
BC022092
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.