RNASE1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD83666A
Western blot analysis of extracts of Mouse pancreas using RNASE1 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of Mouse pancreas using RNASE1 Polyclonal Antibody at dilution of 1:1000.
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Overview

Circle
Product Name
RNASE1 Polyclonal Antibody
Catalog Number
RD83666A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human RNASE1 (NP_937875.1).
Gene ID
6035
Swissprot
P07998
Synonyms
RNASE1RAC1RIB1RNS1
Calculated MW
17 kDa
Observed MW
15 kDa

Applications

Circle
Reactivity
Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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