RNASE1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253050A
Western blot analysis of Mouse pancreas tissue and Rat pancreas tissue lysates using RNASE1 Polyclonal Antibody at dilution of 1:550
Product Name
RNASE1 Polyclonal Antibody
Catalog Number
RD253050A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Immunogen Information
Immunogen
Fusion protein of human RNASE1
Swissprot
P07998
Synonyms
HP-RNasePancreatic ribonucleaseRib 1RIB-1Rib1Ribonuclease 1Ribonuclease ARibonuclease a family 1Ribonuclease pancreaticRibonuclease RNase A family 1Ribonuclease RNase A family 1 pancreaticRNAS1_HUMANRNase 1RNase ARNase UpI-1Rnase1RNAseA
Calculated MW
18 kDa
Observed MW
Refer to figures
Gene Accession
BC005324
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Concentration
0.72 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas