RNASEH2B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89650A
Western blot analysis of extracts of various cell lines using RNASEH2B Polyclonal Antibody at 1:3000 dilution.
Western blot analysis of extracts of mouse thymus using RNASEH2B Polyclonal Antibody at 1:3000 dilution.
Product Name
RNASEH2B Polyclonal Antibody
Catalog Number
RD89650A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).
Immunogen Information
Immunogen
Recombinant fusion protein of human RNASEH2B
Gene ID
79621
Swissprot
Q5TBB1
Synonyms
RNASEH2BAGS2DLEU8
Calculated MW
23kDa
Observed MW
30kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.