E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
Q9Y4L5
Synonyms
BCA2Breast cancer associated gene 2CL469780E3 ubiquitin-protein ligase RNF115Rabring 7RING finger protein 115RN115RNF115Zinc finger protein 364