This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.
Immunogen Information
Immunogen
Recombinant fusion protein of human RNF125 (NP_060301.2).
Gene ID
54941
Swissprot
Q96EQ8
Synonyms
RNF125TNORSTRAC-1TRAC1
Applications
Reactivity
Human
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
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