The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.
Immunogen Information
Immunogen
Synthetic peptide of human RNF5
Swissprot
Q99942
Synonyms
E3 ubiquitin protein ligase RNF5E3 ubiquitin-protein ligase RNF5G16HsRma1NG2OTTHUMP00000029107Protein G16Ram1 homologRING finger protein 5RING5RMA1RNF 5RNF5RNF5
Calculated MW
20 kDa
Gene Accession
NP_008844
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4