This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa.
Immunogen Information
Immunogen
Fusion protein of human ROM1
Swissprot
Q03395
Synonyms
Retinal outer segment membrane protein 1Rod outer segment membrane protein 1ROMROM1ROM1ROSP1RP7Tetraspanin 23Tetraspanin-23Tspan 23Tspan-23TSPAN23