The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm.
Immunogen Information
Immunogen
Synthetic peptide of human RORA
Swissprot
P35398
Synonyms
fhl2aNR1F1Nuclear receptor ROR-alphaNuclear receptor RZR-alphaNuclear receptor subfamily 1 group F member 1RAR-related orphan receptor ARetinoid-related orphan receptor-alphaRoraRORARZR-ALPHARZRA
Calculated MW
59 kDa
Gene Accession
NP_002934
Applications
Reactivity
Human
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4