BXDC1 (Brix domain-containing protein 1) is a 306 amino acid protein encoded by the human gene BXDC1. BXDC1 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region with homology to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes RPF1, RPF2 and SSF1 or SSF2. This complex is required for the biogenesis of the 60S ribosomal subunit.
Immunogen Information
Immunogen
Synthetic peptide of human RPF2
Swissprot
Q9H7B2
Synonyms
bA397G5.4Brix domain containing 1Brix domain containing protein 1Brix domain-containing protein 1BXDC1Homolog of Rpf2Ribosomal processing factor 2 homologRibosome biogenesis protein RPF2 homologRibosome production factor 2 homolog (S. cerevisiae)