RRAD Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78747A
Immunohistochemistry of paraffin-embedded Human brain tissue using RRAD Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using RRAD Polyclonal Antibody at dilution 1:50
Product Name
RRAD Polyclonal Antibody
Catalog Number
RD78747A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.
Immunogen Information
Immunogen
Synthetic peptide of human RRAD
Swissprot
P55042
Synonyms
GTP binding protein RADGTP-binding protein RADRADRADRAD1RAS (RAD and GEM) like GTP binding 3Ras associated with diabetesRas related associated with diabetesREM3RRAD
Gene Accession
NP_004156.1
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas