RRM1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77566A
Western Blot analysis of Hela cell using RRM1 Polyclonal Antibody at dilution of 1:600
Product Name
RRM1 Polyclonal Antibody
Catalog Number
RD77566A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
Immunogen Information
Immunogen
Recombinant protein of human RRM1
Swissprot
P23921
Synonyms
R1Ribonucleoside diphosphate reductase large subunitRibonucleoside diphosphate reductase M1 chainRibonucleoside diphosphate reductase subunit M1Ribonucleoside reductaselarge subunitRibonucleoside-diphosphate reductase large subunitRibonucleoside-di
Calculated MW
90 kDa
Gene Accession
BC006498
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas