RSPO1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Immunohistochemistry of paraffin-embedded Rat lung using RSPO1 Polyclonal Antibody at dilution of  1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Rat lung using RSPO1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse lung using RSPO1 Polyclonal Antibody at dilution of  1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse lung using RSPO1 Polyclonal Antibody at dilution of 1:100 (40x lens).
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Overview

Circle
Product Name
RSPO1 Polyclonal Antibody
Catalog Number
RD267973A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human RSPO1 (NP_001033722.1).
Gene ID
284654
Swissprot
Q2MKA7
Synonyms
RSPO1CRISTIN3RSPO

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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