Rubicon Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Western blot analysis of extracts of mouse brain using Rubicon Polyclonal Antibody at 1:3000 dilution.
Western blot analysis of extracts of mouse brain using Rubicon Polyclonal Antibody at 1:3000 dilution.
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Overview

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Product Name
Rubicon Polyclonal Antibody
Catalog Number
RD87644A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Immunogen Information

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Immunogen
Recombinant fusion protein of human Rubicon
Gene ID
9711
Swissprot
Q92622
Synonyms
RUBCNKIAA0226RUBICONSCAR15
Calculated MW
12kDa/70kDa/79kDa/86kDa
Observed MW
87kDa

Applications

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Reactivity
Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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