The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities.
Immunogen Information
Immunogen
Recombinant Human Protein S100-A12 protein
Gene ID
6283
Swissprot
P80511
Synonyms
CAAF1CAGCCalciterminCalcium-binding protein in amniotic fluid 1Calgranulin CCGRPENRAGEExtracellular newly identified RAGE-binding proteinmigration inhibitory factor-related protein 6MRP6Neutrophil S100 proteinp6Protein S100 A12S1